Increasing incidence of linezolid-intermediate or -resistant, vancomycin-resistant Enterococcus faecium strains parallels increasing linezolid consumption.

نویسندگان

  • Marc H Scheetz
  • Stephanie A Knechtel
  • Michael Malczynski
  • Michael J Postelnick
  • Chao Qi
چکیده

Clinical enterococcal resistance to linezolid is defined by the presence of the G2576T mutation. We evaluated the incidence of genetically proven linezolid resistance among vancomycin-resistant Enterococcus faecium strains and linezolid consumption for a possible association. A relationship was found (r(2) = 0.73, P = 0.03) and predicts increasing resistance with current trends of linezolid use.

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منابع مشابه

Varying linezolid susceptibility of vancomycin-resistant Enterococcus faecium isolates during therapy: a case report.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 52 6  شماره 

صفحات  -

تاریخ انتشار 2008